b , Representative traces of CeA Glp1r fibre photometry recordings showing calcium-dependent fluorescence (465 nm) and calcium-independent, isosbestic fluorescence (405 nm) signals
Yet, a significant change was seen in the fasting blood sugar level before and by the end of the study in the intervention group
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Mechanistically, SGK3 translocated to the nucleus upon glucocorticoid stimulation, interacted with and phosphorylated the BRG1 subunit of the BAF complex, and prevented BRG1 degradation, promoting chromatin remodeling necessary for adipogenesis
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